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Eisai's Alzheimer's Drug Leqembi Grows 27% as Quarterly Profit Jumps 26%

Lenvima, Leqembi and Dayvigo again did the heavy lifting for Eisai's first quarter, with Leqembi's Americas sales up 71% masking a China pullback tied to last year's distributor stocking, while the drugmaker left its full-year targets exactly where it set them in May.

Aug 3, 20262 min readEisai Co., Ltd.4523
Close-up of a subcutaneous auto-injector pen and glass medicine vials on a clinical tray, representing a pharmaceutical therapy.

Eisai's fiscal first quarter, the three months to June 2026, produced the kind of numbers that might tempt a company to raise its outlook: revenue rose 15.6% to ¥234.33bn and operating profit climbed 19.2% to ¥24.73bn. Net profit attributable to shareholders grew 26% to ¥18.24bn. Eisai left its full-year forecast untouched instead, sticking with the ¥883.5bn revenue and ¥70.0bn operating-profit targets it published on 15 May 2026, up 7.0% and 58.6% respectively from the prior year.

The growth again traces back to the same three drugs Eisai calls its "3L" lineup. Cancer treatment Lenvima brought in ¥97.3bn, up 15.9%. Alzheimer's drug Leqembi rose 26.7% to ¥29.3bn, and insomnia treatment Dayvigo grew 37.9% to ¥18.9bn.

Eisai's core growth drugs: quarter versus full-year target
Figures for the three months to June 2026, compared with the year-earlier quarter and Eisai's unchanged full-year target.
ProductQ1 salesYoY growthFull-year target
Lenvima¥97.3bn+15.9%¥345.0bn
Leqembi¥29.3bn+26.7%¥143.5bn
Dayvigo¥18.9bn+37.9%¥73.5bn

Leqembi's headline figure hides a lopsided regional story. American sales jumped 70.5% to ¥15.5bn, from ¥9.1bn a year earlier, as wider early-Alzheimer's diagnosis and blood-based biomarker testing expanded the pool of eligible patients. Chinese sales fell 37.3% to ¥4.8bn, but Eisai attributes the drop to a distorted comparison: distributors there had stocked up ahead of demand a year earlier, inflating the base. Eisai also opened new Leqembi markets in June, launching in Belgium and Australia, then in Brazil and India. In the US, regulators approved an under-the-skin, initial-therapy version of the drug, branded Leqembi IQLIK, on 13 July; Eisai plans to launch it in late August, betting that a home-administered injection will widen access beyond infusion clinics.

None of this came free. Selling costs rose partly because Eisai's profit-sharing payment to Merck & Co. on Lenvima sales climbed to ¥44.3bn from ¥36.0bn a year earlier, a mechanical consequence of Lenvima's own growth under the companies' co-promotion agreement. Stripped of one-off items, core operating profit rose a narrower 13.9% to ¥24.7bn.

On Eisai's own scorecard, the quarter left it at 26.5% of the full-year revenue target and 35.3% of the operating-profit target, both ahead of a straight-line quarterly pace. Management chose to hold its forecast rather than lift it, leaving room to point to currency assumptions, tariff policy and an upcoming US regulatory decision on an expanded Lenvima combination, due 4 October 2026, before revisiting the numbers later in the year.